Nikki Glaser wants non-Ozempic users to reserve their judgment about the medication.
The comedienne and recent Golden Globes host visited The Tonight Show Starring Jimmy Fallon on Monday (March 24), and gave her opinion on the medication around the four-minute mark below. While Ozempic is popularly used for weight loss, it originated as a treatment for Type 2 diabetes. Celebrities who've gone public about their use of Ozempic include Amy Schumer, Kelly Osbourne, and Tracy Morgan. The injectable medication contains semaglutide, which increases insulin levels and regulates appetite.
Glaser, who has plans to get a facelift, began with talking about "investing" in beauty, adding that "people treat you better when you're hotter." Fallon then asked the 40-year-old about her thoughts are Ozempic.
"Oh, I love it, I love it. I’m like, do it, do it. I have no judgment. If you want to do Ozempic, hell yeah, girl," Glaser told Fallon. "I want people to feel more comfortable talking about doing it, because I feel like there’s, like, this shame—and the shame is only from thin people who want you to stay fat. Like that's really where it's coming from."
"They are so mad that you're getting thin now, because that's all they have, right? They are so mad, but they can't say it. They just go, 'No! You’re stealing medicine from diabetics who need it.' Like, that’s their excuse," she continued. "It's suddenly all these thin, white women are like 'diabetics need their meds.’ No, I think you’re upset that Kathy Bates has a thigh gap. That’s more what it could be about, I think."
But among Ozempic's famous critics is actress Jameela Jamil, who struggled with an eating disorder as a teenager and throughout her twenties.
"May I have the strength through this era of Ozempic heroin chic, in my industry to keep up this good work I did on my brain throughout 2025," she wrote in an Instagram post in December. "I would rather leave this industry than get dragged back."
